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Large meals overwhelm a digestive system already slowed by GLP-1 receptor activation

NMDAN-methyl-D-aspartate receptor

Retatrutide has shown common side effects similar to other GLP-1 receptor agonists, including: Nausea Vomiting Diarrohea Constipation Abdominal discomfort or bloating Some trial participants experienced a slight increase in resting heart rate, which has also been observed with other GLP-1 receptor agonists

Hyperbilirubin results were not due to chronic hepatic disease or alcohol consumption

Our findings align with and further extend prior meta-analyses that have shown benefits of GLP-1 receptor agonists in PCOS ( This study has several strengths